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Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? August and September are the most popular months to cruise between Spain and Italy and there are 212 departures available from sixteen of the world's leading cruise lines.
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111 Cruises (212 Cruise Departures)
22 Day Barcelona to Venice with Silversea
Cruise

22 Days (21 Nights) Barcelona to Venice
Cruise Line: Silversea
Ship: Silver Moon
Departure: 16 August 2024
Countries Visited: Spain, France, Italy, Sardinia (+4 more), Sicily, Malta, Montenegro, Croatia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$21,780
BALCONY
$24,849
SUITE
-
From 21,780
View Trip
17 Day Barcelona to Civitavecchia with Silversea
Cruise

17 Days (16 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 06 July 2025
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,513
From 18,513
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 11 July 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,516
SUITE
$43,029
From 24,516
View Trip
11 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Barcelona to Venice
Ship: Norwegian Escape
Departure: 11 August 2024
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
INSIDE
$2,920
OCEANVIEW
$3,486
BALCONY
$3,562
SUITE
$4,175
From 2,920
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 05 August 2024
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$2,317
OCEANVIEW
$2,345
BALCONY
$2,664
SUITE
$3,619
Save 916
From 1,959
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 11 July 2024
Countries Visited: Spain, Italy, France
Exclusive Offer
INSIDE
-
OCEANVIEW
$2,278
BALCONY
$2,737
SUITE
$7,106
Save 2,894
From 2,278
View Trip
8 Day A Journey From Tarragona To Rome with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 23 September 2024
Countries Visited: Spain, France, Corsica, Sardinia (+1 more), Italy
Exclusive DealUnique Escapes
INSIDE
-
OCEANVIEW
-
BALCONY
$6,014
SUITE
$7,311
From 6,014
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: May 2026 to Jun 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
Exclusive Deal
INSIDE
$2,380
OCEANVIEW
$2,578
BALCONY
$2,924
SUITE
$7,231
From 2,380
View Trip
21 Day France & Spanish Treasures with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 October 2024
Countries Visited: Spain, France, Tunisia, Italy (+2 more), Sicily, Malta
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$20,809
SUITE
-
From 20,809
View Trip
12 Day Europe - Western Mediterranean - Barcelona with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Barcelona to Venice
Ships: Norwegian Breakaway, Norwegian Escape
Departures: Sep 2024 to Sep 2025
Countries Visited: Spain, France, Italy, Sicily (+3 more), Malta, Greece, Croatia
Exclusive Solo Offer
INSIDE
$3,685
OCEANVIEW
$4,297
BALCONY
$5,367
SUITE
$5,673
From 3,685
View Trip
13 Day Best Of The Med Voyage with Azamara Cruises
Cruise

13 Days (12 Nights) Barcelona to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 13 July 2024
Countries Visited: Spain, France, Monaco, Italy (+3 more), Montenegro, Croatia, Slovenia
Circle Club Voyage
INSIDE
$3,593
OCEANVIEW
$3,217
BALCONY
$4,545
SUITE
$7,381
From 3,217
View Trip
29 Day Mediterranean And Greek Islands with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 May 2026
Countries Visited: Spain, Greece, Turkey, France (+3 more), Italy, Corsica, Sicily
Exclusive Deal
INSIDE
$4,414
OCEANVIEW
$4,810
BALCONY
$5,602
SUITE
$14,859
From 4,414
View Trip
11 Day Blooming Mediterranean with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 08 May 2025
Countries Visited: Spain, Tunisia, Malta, Greece (+2 more), Sicily, Italy
Cabin Upgrade Offer
INSIDE
$5,488
OCEANVIEW
-
BALCONY
$6,557
SUITE
$10,765
From 5,488
View Trip
21 Day Spain, Morocco & Mediterranean Overture with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Gibraltar, Morocco (+4 more), Monaco, Italy, Corsica, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$15,755
SUITE
$28,714
From 15,755
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise

8 Days (7 Nights) Barcelona to Naples
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,745
OCEANVIEW
$2,132
BALCONY
$2,409
SUITE
$2,904
From 1,745
View Trip
23 Day Mediterranean Magic & Tyrrhenian Treasures with Seabourn
Cruise

23 Days (22 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 31 August 2024
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$22,890
SUITE
-
From 22,890
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Alicante to Rome
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 26 November 2024
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$778
SUITE
$1,421
From 778
View Trip
9 Day Mediterranean Marvels & Matches: Monte Carlo Masters with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Venture
Departure: 05 April 2025
Countries Visited: Spain, France, Monaco, Italy
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,844
SUITE
$21,298
From 8,844
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 July 2025
Countries Visited: Spain, Corsica, France, Italy
Exclusive Deal
INSIDE
$1,635
OCEANVIEW
$1,734
BALCONY
$1,981
SUITE
$4,258
From 1,635
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departures: Sep 2024 to Oct 2024
Countries Visited: Spain, France, Corsica, Italy (+2 more), Malta, Sicily
Exclusive Offer
INSIDE
$2,733
OCEANVIEW
$3,791
BALCONY
$4,683
SUITE
$9,981
Save 3,467
From 2,733
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Valencia to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 27 November 2024
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$600
BALCONY
$728
SUITE
$1,421
From 600
View Trip
8 Day Etruscan Waterways with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
$3,872
OCEANVIEW
$4,714
BALCONY
$5,248
SUITE
$7,298
Save 2,028
From 3,872
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
Exclusive Deal
INSIDE
$2,677
OCEANVIEW
$3,122
BALCONY
$3,568
SUITE
$8,518
From 2,677
View Trip
29 Day Istanbul, Greek Islands And Mediterranean with Cunard
Cruise

29 Days (28 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+3 more), France, Greece, Turkey
Exclusive Deal
INSIDE
$4,909
OCEANVIEW
$5,305
BALCONY
$6,097
SUITE
$17,829
From 4,909
View Trip
13 Day Vita Est Bona with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 24 August 2024
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sardinia
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,579
SUITE
$11,723
Save 11,141
From 10,579
View Trip
6 Day Barcelona to Rome with Silversea
Cruise

6 Days (5 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 22 June 2024
Countries Visited: Spain, France, Italy
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,692
From 10,692
View Trip
11 Day Italian Riviera & France with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 08 June 2024
Countries Visited: Spain, Corsica, Italy, France (+3 more), Sardinia, Malta, Sicily
Exclusive Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$9,496
SUITE
$10,967
Save 7,046
From 10,967
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+2 more), Italy, Croatia
Save And Sail Offer
INSIDE
$1,567
OCEANVIEW
$1,914
BALCONY
$2,844
SUITE
$4,280
From 1,567
View Trip
10 Day A Journey from Barcelona to Rome with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 April 2025
Countries Visited: Spain, Sardinia, Tunisia, Sicily (+1 more), Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,118
SUITE
$9,930
From 8,118
View Trip
6 Day France & Italy Cruise with Royal Caribbean
Cruise

6 Days (5 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 12 May 2025
Countries Visited: Spain, Corsica, Italy, Sicily
Exclusive Deal
INSIDE
$1,522
OCEANVIEW
$1,993
BALCONY
$2,050
SUITE
$3,255
Save 589
From 1,319
View Trip
Results: 61-90 of 111

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