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Cruises From Santa Cruz de Tenerife

Choose from 57 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Genoa, Lisbon, Madeira and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 194 departures available from four leading cruise lines.
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21 Days
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57 Cruises (194 Cruise Departures)
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,603
OCEANVIEW
$1,821
BALCONY
$2,494
SUITE
$3,415
From 1,603
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,525
OCEANVIEW
$3,154
BALCONY
$3,756
SUITE
-
From 2,525
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,206
From 693
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
INSIDE
$1,653
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$3,927
From 1,653
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$2,067
BALCONY
$2,471
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2024 to Dec 2025
Countries Visited: Spain, Portugal
INSIDE
$1,626
OCEANVIEW
$2,216
BALCONY
$2,649
SUITE
$7,793
From 1,626
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,867
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
$4,299
From 1,633
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 07 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,372
SUITE
-
From 1,497
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 20 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
-
From 1,633
View Trip
11 Day Canary Islands & Spanish coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,242
BALCONY
-
SUITE
$14,202
Save 2,603
From 10,242
View Trip
12 Day Mediterranean with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 27 October 2024
Countries Visited: Spain, Portugal, France, Italy (+1 more), Morocco
Early Booking Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$2,615
SUITE
-
From 2,615
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 06 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,372
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2024 to Mar 2025
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$959
OCEANVIEW
$1,177
BALCONY
$1,850
SUITE
$2,771
From 959
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
INSIDE
$2,059
OCEANVIEW
$2,451
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
11 Day Archipelagos To Alcazars with Oceania Cruises
Cruise

11 Days (10 Nights) Santa Cruz de Tenerife to Lisbon
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2025
Countries Visited: Spain, Portugal, Morocco, Gibraltar
Cabin Upgrade Offer
INSIDE
$5,596
OCEANVIEW
$6,814
BALCONY
$6,814
SUITE
$8,497
From 5,596
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 13 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,309
OCEANVIEW
$4,097
BALCONY
$4,679
SUITE
$7,154
From 3,309
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
INSIDE
$2,705
OCEANVIEW
$3,402
BALCONY
$4,084
SUITE
-
From 2,705
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 14 December 2024
Countries Visited: Spain, Portugal
INSIDE
$3,309
OCEANVIEW
$3,978
BALCONY
$4,778
SUITE
-
From 3,309
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$663
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 663
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
INSIDE
$3,366
OCEANVIEW
$3,906
BALCONY
$4,885
SUITE
-
From 3,366
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
INSIDE
$1,703
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,703
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
INSIDE
$1,762
OCEANVIEW
$1,976
BALCONY
$2,657
SUITE
$4,744
From 1,762
View Trip
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