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Cruises From Santa Cruz de Tenerife

Choose from 59 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Genoa, Lisbon, Madeira and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 196 departures available from five leading cruise lines.
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4 Days
21 Days
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59 Cruises (196 Cruise Departures)
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,772
OCEANVIEW
$2,038
BALCONY
$2,621
SUITE
$4,353
From 1,772
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Dec 2024 to Dec 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,087
From 693
View Trip
4 Day Canary Islands And Madeira with MSC Cruises
Cruise

4 Days (3 Nights) Santa Cruz de Tenerife to Madeira
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$510
OCEANVIEW
$599
BALCONY
$847
SUITE
$1,223
From 510
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 25 October 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,257
OCEANVIEW
$2,768
BALCONY
$3,627
SUITE
-
From 2,257
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,471
SUITE
-
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,883
OCEANVIEW
$3,899
BALCONY
$4,451
SUITE
$9,945
From 2,883
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$712
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 712
View Trip
11 Day Canary Islands & Spanish coast with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,242
BALCONY
-
SUITE
$14,202
Save 2,603
From 10,242
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$2,097
BALCONY
$2,471
SUITE
-
From 1,497
View Trip
13 Day Jewels of Spain and Morocco with Scenic
New ReleaseCruise

13 Days (12 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2026
Countries Visited: Spain, Morocco, Algeria
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,073
SUITE
$26,992
Save 5,172
From 17,073
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,187
OCEANVIEW
$1,405
BALCONY
-
SUITE
-
From 1,187
View Trip
21 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 13 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
$2,705
OCEANVIEW
$3,402
BALCONY
$4,084
SUITE
-
From 2,705
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
$4,299
From 1,633
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,505
OCEANVIEW
$2,237
BALCONY
$2,404
SUITE
-
From 1,505
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 22 December 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,603
OCEANVIEW
$1,821
BALCONY
$2,494
SUITE
$3,415
From 1,603
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
$4,196
BALCONY
-
SUITE
-
From 4,196
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,748
SUITE
$3,936
From 1,497
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
$1,515
OCEANVIEW
$1,839
BALCONY
$2,599
SUITE
-
From 1,515
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 27 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,366
OCEANVIEW
$3,906
BALCONY
$4,885
SUITE
-
From 3,366
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Feb 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,471
SUITE
$4,332
From 1,497
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$693
OCEANVIEW
$969
BALCONY
$1,315
SUITE
$2,206
From 693
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+2 more), Italy, Croatia
Save And Sail Offer
INSIDE
$1,567
OCEANVIEW
$1,914
BALCONY
$2,844
SUITE
$4,280
From 1,567
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 24 October 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,257
OCEANVIEW
$2,768
BALCONY
$3,627
SUITE
-
From 2,257
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
$3,790
From 1,505
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 07 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,372
SUITE
-
From 1,497
View Trip
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