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Cruises From Santa Cruz de Tenerife

Choose from 59 unique cruises starting in Santa Cruz de Tenerife, and travelling to Barcelona, Bari, Genoa, Lisbon, Madeira and more. December is the most popular month to join a cruise from Santa Cruz de Tenerife and you can select from 196 departures available from five leading cruise lines.
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4 Days
21 Days
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59 Cruises (196 Cruise Departures)
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
-
From 1,633
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 31 October 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,059
OCEANVIEW
$2,550
BALCONY
$3,301
SUITE
$5,368
From 2,059
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,762
OCEANVIEW
$1,976
BALCONY
$2,657
SUITE
$4,744
From 1,762
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 24 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,207
OCEANVIEW
$1,405
BALCONY
$2,078
SUITE
$2,999
From 1,207
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Dec 2024 to Dec 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,087
From 693
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
View Trip
13 Day Jewels of Spain and Morocco with Scenic
New ReleaseCruise

13 Days (12 Nights) Santa Cruz de Tenerife to Barcelona
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 03 May 2026
Countries Visited: Spain, Morocco, Algeria
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,073
SUITE
$26,992
Save 5,172
From 17,073
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
$4,196
BALCONY
-
SUITE
-
From 4,196
View Trip
20 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

20 Days (19 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 14 March 2026
Countries Visited: Spain, Portugal, Gibraltar, Italy (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
$2,525
OCEANVIEW
$3,154
BALCONY
$3,756
SUITE
-
From 2,525
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$663
OCEANVIEW
$969
BALCONY
$1,413
SUITE
$2,095
From 663
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 21 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,505
OCEANVIEW
$1,970
BALCONY
$2,404
SUITE
$3,790
From 1,505
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
$1,515
OCEANVIEW
$1,839
BALCONY
$2,599
SUITE
-
From 1,515
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,148
OCEANVIEW
$4,055
BALCONY
$4,885
SUITE
$7,793
From 3,148
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$693
OCEANVIEW
$969
BALCONY
$1,315
SUITE
$2,206
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 13 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,111
OCEANVIEW
$4,097
BALCONY
$4,679
SUITE
$10,292
From 3,111
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 November 2024
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$1,187
OCEANVIEW
$1,405
BALCONY
-
SUITE
-
From 1,187
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Mar 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,633
OCEANVIEW
$2,055
BALCONY
$2,657
SUITE
$4,744
From 1,633
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2024 to Dec 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,626
OCEANVIEW
$2,216
BALCONY
$2,649
SUITE
$7,793
From 1,626
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 28 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,883
OCEANVIEW
$3,750
BALCONY
$4,451
SUITE
-
From 2,883
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 26 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,653
OCEANVIEW
$1,959
BALCONY
$2,621
SUITE
$3,927
From 1,653
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,497
OCEANVIEW
$1,998
BALCONY
$2,748
SUITE
$3,936
From 1,497
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 14 December 2024
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,111
OCEANVIEW
$3,978
BALCONY
$4,679
SUITE
-
From 3,111
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 01 November 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,059
OCEANVIEW
$2,451
BALCONY
$3,380
SUITE
$5,368
From 2,059
View Trip
8 Day Canary Islands And Madeira with MSC Cruises
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2024 to Feb 2025
Countries Visited: Spain, Portugal
Save And Sail Offer
INSIDE
$959
OCEANVIEW
$1,177
BALCONY
$1,850
SUITE
$2,771
From 959
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 24 October 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$2,257
OCEANVIEW
$2,768
BALCONY
$3,627
SUITE
-
From 2,257
View Trip
8 Day Canary Islands with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Oct 2024 to Oct 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$693
OCEANVIEW
$1,049
BALCONY
$1,315
SUITE
$2,206
From 693
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departure: 19 December 2025
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$3,643
OCEANVIEW
$4,104
BALCONY
$5,132
SUITE
-
From 3,643
View Trip
15 Day Canary Islands with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Santa Cruz de Tenerife to Santa Cruz de Tenerife
Ship: Azura
Departures: Nov 2025 to Feb 2026
Countries Visited: Spain, Portugal
Exclusive Deal
INSIDE
$1,633
OCEANVIEW
$1,976
BALCONY
$2,538
SUITE
$4,299
From 1,633
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise

12 Days (11 Nights) Santa Cruz de Tenerife to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+2 more), Italy, Croatia
Save And Sail Offer
INSIDE
$1,567
OCEANVIEW
$1,914
BALCONY
$2,844
SUITE
$4,280
From 1,567
View Trip
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