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Cruises From San Diego

Choose from 64 unique cruises starting in San Diego, and travelling to Fort Lauderdale, Miami, New York, Papeete, Tahiti and more. April is the most popular month to join a cruise from San Diego and you can select from 93 departures available from four leading cruise lines.
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52 Days
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64 Cruises (93 Cruise Departures)
16 Day Panama Canal with Holland America
Cruise

16 Days (15 Nights) San Diego to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 27 February 2026
Countries Visited: USA, Mexico, Guatemala, Panama (+2 more), Colombia, Bahamas
Have It All Offer
INSIDE
$5,187
OCEANVIEW
$5,682
BALCONY
$6,870
SUITE
$8,652
From 5,187
View Trip
15 Day Mexican Riviera & Baja Peninsula with Holland America
Cruise

15 Days (14 Nights) San Diego to San Diego
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Zaandam
Departures: Nov 2025 to Apr 2026
Countries Visited: USA, Mexico
Have It All Offer
INSIDE
$3,623
OCEANVIEW
$4,068
BALCONY
$4,811
SUITE
$8,078
From 3,623
View Trip
21 Day Panoramic Panama Canal with Oceania Cruises
Cruise

21 Days (20 Nights) San Diego to New York
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 03 July 2025
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Colombia, Cayman Islands
Cabin Upgrade Offer
INSIDE
$8,828
OCEANVIEW
$8,828
BALCONY
$10,046
SUITE
$19,698
From 8,828
View Trip
15 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

15 Days (14 Nights) San Diego to Miami
Ship: Norwegian Jade
Departure: 18 October 2025
Countries Visited: USA, Mexico, Guatemala, Panama (+2 more), Colombia, Cayman Islands
Exclusive Solo Offer
INSIDE
$3,916
OCEANVIEW
$4,605
BALCONY
$6,363
SUITE
$7,127
From 3,916
View Trip
Results: 61-64 of 64

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Travel Styles

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Trip Lengths

1 Month

Departure Months

October 2024 November 2024 December 2024 January 2025 February 2025 March 2025 April 2025 May 2025 July 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026

Cities

Amsterdam Anchorage Baltimore Boston Cape Liberty Fort Lauderdale Galveston Honolulu Los Angeles Miami New Orleans New York Orlando San Diego San Francisco San Juan Seattle Seward Tampa

Routes

Anchorage to Vancouver Baltimore to Baltimore Barcelona to Fort Lauderdale Barcelona to Miami Boston to Montreal Boston to Quebec City Boston to Boston Bridgetown to Miami Cape Liberty to Cape Liberty Fort Lauderdale to Los Angeles Fort Lauderdale to London Fort Lauderdale to Barcelona Fort Lauderdale to Fort Lauderdale Fort Lauderdale to San Diego Fort Lauderdale to Vancouver Galveston to Galveston Honolulu to Tahiti Lisbon to Miami London to Fort Lauderdale London to New York Los Angeles to Miami Los Angeles to Vancouver Los Angeles to Los Angeles Miami to San Juan Miami to Los Angeles Miami to Rome Miami to Bridgetown Miami to Panama City Miami to Barcelona Miami to Miami Miami to London Montreal to Boston Montreal to New York New Orleans to New Orleans New York to Montreal New York to New York New York to Quebec City New York to London Orlando to Orlando Panama City to Miami Quebec City to Boston Quebec City to New York Rome to Miami Rome to Fort Lauderdale San Diego to Vancouver San Diego to San Diego San Francisco to San Francisco Seattle to Vancouver Seattle to Seattle Seward to Vancouver Sydney to Honolulu Tampa to Tampa Vancouver to Los Angeles Vancouver to Honolulu Vancouver to Seward Vancouver to Seattle

Country Routes

Argentina to USA Australia to USA Barbados to USA Canada to USA England to USA France to USA French Polynesia to USA Greece to USA Holland to USA Iceland to USA Italy to USA Japan to USA Panama to USA Portugal to USA Puerto Rico to USA Spain to USA USA to Portugal USA to Germany USA to Puerto Rico USA to Argentina USA to Australia USA to Barbados USA to Canada USA to England USA to French Polynesia USA to Italy USA to Japan USA to Panama USA to Peru USA to Spain

Cruise Lines

Abercrombie & Kent APT Azamara Celebrity Cruises Celestyal Cruises Cunard Emerald Cruises Explora Journeys G Adventures Heritage Expeditions Holland America Hurtigruten Intrepid MSC Cruises Norwegian Cruise Line Oceania P&O Cruises P&O Cruises Worldwide Ponant Princess Regent Seven Seas Royal Caribbean Scenic Seabourn Silversea Tauck Travelmarvel Viking Virgin Voyages

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