Home > Tours > Latin America Tours > Central America Tours > Panama Tours & Cruises > October 2025

Panama Tours & Cruises Starting In October 2025

If you're looking at joining a tour to Panama in October 2025, we have 18 unique cruises, small group tours and adventures with 228 departures from the world's leading tour operators departing in October.
Filter Results
Departures (October 2025)
< September 2025 November 2025 >
Duration
11 Days
47 Days
Types
Start & End Cities
Operators
Show More...
Price
$1,500pp
$124,495pp
Countries
Show More...
Filter Results
18 Trips (228 Trip Departures)
12 Day Costa Rica & Panama Discovery with Intrepid Travel
Tour

12 Days San Jose to Panama City
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Costa Rica, Panama
Limited Time Sale
Save 343
From 1,578
View Trip
14 Day Cycle Nicaragua to the Panama Canal with Explore!
Tour

14 Days Granada to Panama City
Operated By: Explore!
Departures: Oct 2024 to Nov 2025
Trip Styles: Adventure, Small Group, Cycling
Countries Visited: Costa Rica, Panama, Nicaragua
Exclusive Savings
Save 147
From 7,203
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (2)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Feb 2025 to Feb 2026
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+2 more), Panama, Aruba
Exclusive Deal
INSIDE
$2,593
OCEANVIEW
$2,839
BALCONY
$3,689
SUITE
$4,698
From 2,593
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Fort Lauderdale to Panama City
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$5,440
SUITE
$8,410
Save 1,230
From 5,440
View Trip
17 Day Panama Canal - Ocean to Ocean with Princess
Cruise
 (2)

17 Days (16 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Princess
Ships: Coral Princess, Island Princess
Departures: Dec 2024 to Oct 2025
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+2 more), Panama, Curacao
Exclusive Deal
INSIDE
$2,766
OCEANVIEW
$3,028
BALCONY
$4,079
SUITE
$5,869
From 2,766
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Fort Lauderdale to Santiago
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Oct 2024 to Oct 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+2 more), Peru, Chile
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$14,845
SUITE
$20,785
Save 1,150
From 14,845
View Trip
16 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

16 Days (15 Nights) Los Angeles to Miami
Ships: Norwegian Bliss, Norwegian Encore (+1 more), Norwegian Joy
Departures: Oct 2025 to Feb 2026
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
Exclusive Solo Offer
INSIDE
$3,586
OCEANVIEW
$4,580
BALCONY
$5,139
SUITE
$5,903
From 3,586
View Trip
19 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

19 Days (18 Nights) San Francisco to Miami
Ship: Norwegian Joy
Departure: 02 October 2025
Countries Visited: USA, Mexico, Guatemala, Costa Rica (+2 more), Panama, Colombia
INSIDE
$4,360
OCEANVIEW
$5,584
BALCONY
$5,965
SUITE
$6,959
From 4,360
View Trip
28 Day Amazing Central America with Intrepid Travel
Tour

28 Days Antigua to Panama City
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Guatemala, Honduras, El Salvador, Nicaragua (+2 more), Costa Rica, Panama
Limited Time Sale
Save 763
From 3,480
View Trip
15 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

15 Days (14 Nights) San Diego to Miami
Ship: Norwegian Jade
Departure: 18 October 2025
Countries Visited: USA, Mexico, Guatemala, Panama (+2 more), Colombia, Cayman Islands
Exclusive Solo Offer
INSIDE
$3,619
OCEANVIEW
$4,308
BALCONY
$6,066
SUITE
$6,830
From 3,619
View Trip
13 Day Panama Canal Sunfarer with Holland America
Cruise
 (2)

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Oct 2024 to Mar 2026
Countries Visited: USA, Bahamas, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
Have It All Offer
INSIDE
$3,212
OCEANVIEW
$3,806
BALCONY
$4,845
SUITE
$5,815
From 3,212
View Trip
24 Day Panama Canal & Pacific Coast with Princess
Cruise
 (1)

24 Days (23 Nights) Vancouver to Fort Lauderdale
Cruise Line: Princess
Ship: Coral Princess
Departure: 21 October 2025
Countries Visited: Canada, USA, Mexico, Nicaragua (+3 more), Costa Rica, Panama, Aruba
Exclusive Deal
INSIDE
$4,189
OCEANVIEW
$4,593
BALCONY
$5,952
SUITE
$6,878
From 4,189
View Trip
13 Day Panama Canal with Costa Rica & Caribbean with Princess
Cruise

13 Days (12 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ships: Caribbean Princess, Emerald Princess
Departures: Oct 2024 to Mar 2026
Countries Visited: USA, Aruba, Curacao, Colombia (+3 more), Panama, Costa Rica, Cayman Islands
Exclusive Deal
INSIDE
$1,740
OCEANVIEW
$1,996
BALCONY
$2,968
SUITE
$3,591
From 1,740
View Trip
44 Day Best of Central America with Intrepid Travel
Tour
 (1)

44 Days Playa del Carmen to Panama City
Operated By: Intrepid Travel
Departures: Aug 2024 to Nov 2025
Trip Styles: Adventure, Small Group
Countries Visited: Mexico, Belize, Guatemala, Honduras (+4 more), El Salvador, Nicaragua, Costa Rica, Panama
Limited Time Sale
Save 1,233
From 5,466
View Trip
18 Day West Indies & Panama Canal Passage with Viking Cruises
New ReleaseCruise
 (5)

18 Days (17 Nights) Los Angeles to San Juan
Cruise Line: Viking Cruises
Ship: Viking Sea
Departure: 02 October 2025
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+4 more), Panama, Colombia, Curacao, Puerto Rico
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$19,795
Save 1,100
From 9,895
View Trip
41 Day The Americas & Antarctic Explorer with Viking Cruises
Cruise

41 Days (40 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Polaris
Departures: Oct 2024 to Oct 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+4 more), Peru, Chile, Argentina, Antarctica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$45,436
SUITE
$64,345
Save 2,459
From 45,436
View Trip
22 Day Panama Canal Sunfarer & Southern Caribbean Seafarer with Holland America
Cruise
 (2)

22 Days (21 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Rotterdam
Departures: Oct 2025 to Mar 2026
Countries Visited: USA, Bahamas, Curacao, Colombia (+5 more), Panama, Costa Rica, Cayman Islands, Bonaire, Aruba
Have It All Offer
INSIDE
$5,986
OCEANVIEW
$7,322
BALCONY
$7,916
SUITE
$10,094
From 5,986
View Trip
47 Day The Americas, Chile & Antarctica with Viking Cruises
Cruise

47 Days (46 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 13 October 2025
Countries Visited: USA, Mexico, Panama, Ecuador (+6 more), Peru, Chile, Argentina, Antarctica, South Georgia Island, Falkland Islands
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$53,356
SUITE
$79,195
Save 2,539
From 53,356
View Trip
Results: 18 results

No Results found. Try changing your search filters.




Trips found! Scroll up to view

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

Travel Styles

Active Adventures Cycling Tours Locally Guided Tours Small Group Tours Wildlife Tours

Trip Lengths

1 Month 10 Day 2 Week 3 Week 4 Week

Departure Months

June 2024 July 2024 August 2024 September 2024 October 2024 November 2024 December 2024 January 2025 February 2025 March 2025 April 2025 May 2025 June 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 September 2026 October 2026

Countries

Chile Colombia Costa Rica Ecuador Peru USA

Cities

Los Angeles San Francisco San Jose

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

© 2010-2024. Global Journeys. You're viewing our site in Australian dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map | We're Hiring!

Global Journeys Pty Ltd. Member of The Australian Travel Industry Association (AITA) & ATAS Travel Accredited (No. A11351).

Travel Industry Associations