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Mediterranean Luxury Cruises

Explore the best luxury cruises in the Mediterranean. Choose from 456 unique cruise itineraries from 10 leading cruise lines. May is the most popular month to join a luxury cruise in the Mediterranean with 544 departures starting between June 2024 and April 2027.
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456 Cruises (544 Cruise Departures)
10 Day Exquisite Mediterranean with Regent Seven Seas
Cruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 05 September 2024
Countries Visited: Italy, Sicily, Greece, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,315
SUITE
$14,790
Save 4,225
From 13,315
View Trip
21 Day France, Italy & Maltese Gems with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Italy, Corsica (+3 more), Sardinia, Malta, Tunisia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,092
SUITE
$28,714
From 16,092
View Trip
8 Day Italy, France And Spain with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 July 2024
Countries Visited: Italy, France, Spain
Exclusive Deal
INSIDE
$2,179
OCEANVIEW
$2,278
BALCONY
$2,674
SUITE
$5,149
From 2,179
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,315
From 18,315
View Trip
12 Day Antiquity To Anatolia with Oceania Cruises
Cruise

12 Days (11 Nights) Rome to Istanbul
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 29 October 2025
Countries Visited: Italy, Sicily, Greece, Turkey
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,924
SUITE
$10,844
Save 2,056
From 6,924
View Trip
18 Day Discover the Ancient Treasures of the Mediterranean & Red Sea with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Cairo to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Kaia
Departure: 07 April 2027
Countries Visited: Egypt, Jordan, Israel, Cyprus (+2 more), Turkey, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
$18,355
BALCONY
-
SUITE
$24,220
Save 6,685
From 18,355
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$1,635
OCEANVIEW
$1,783
BALCONY
$2,179
SUITE
$4,654
From 1,635
View Trip
13 Day Myths & Heroes with Regent Seven Seas
Cruise

13 Days (12 Nights) Barcelona to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 24 September 2025
Countries Visited: Spain, France, Italy, Sicily (+3 more), Greece, Croatia, Montenegro
Exclusive Solo OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,240
SUITE
$15,754
Save 7,720
From 13,240
View Trip
11 Day Riviera & Mediterranean Jewels with Seabourn
Cruise

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Nov 2025
Countries Visited: Italy, Malta, Tunisia, France (+1 more), Spain
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,760
SUITE
$15,913
From 8,760
View Trip
15 Day Ultimate Treasures of Spain & the Mediterranean with Scenic
New ReleaseCruise

15 Days (14 Nights) Malaga to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 April 2025
Countries Visited: Spain, Gibraltar, France, Monaco
Earlybird SavingExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$17,695
SUITE
$24,696
Save 7,635
From 17,695
View Trip
21 Day Discover the Yachting Treasures of the Mediterranean with Emerald Cruises
New ReleaseCruise

21 Days (20 Nights) Santa Cruz de Tenerife to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 15 April 2026
Countries Visited: Spain, Morocco, Corsica, Sardinia (+2 more), Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$19,246
BALCONY
-
SUITE
$26,918
Save 6,694
From 19,246
View Trip
9 Day Flavors Of Luxury with Regent Seven Seas
Cruise

9 Days (8 Nights) Valletta to Monte Carlo
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 14 September 2024
Countries Visited: Malta, Spain, France, Corsica (+1 more), Monaco
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,190
SUITE
$8,089
Save 9,000
From 7,190
View Trip
21 Day Mediterranean Magic & Tyrrhenian Treasures with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Barcelona
Cruise Line: Seabourn
Ship: Ovation
Departure: 15 April 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$16,092
SUITE
$29,135
From 16,092
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,909
From 18,909
View Trip
8 Day Monte Carlo to Rome with Silversea
Cruise

8 Days (7 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 July 2025
Countries Visited: Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,801
From 9,801
View Trip
12 Day Lisbon to Monte Carlo with Silversea
Cruise

12 Days (11 Nights) Lisbon to Monte Carlo
Cruise Line: Silversea
Ship: Silver Spirit
Departure: 24 September 2025
Countries Visited: Portugal, Spain, France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$13,365
BALCONY
$15,543
SUITE
$14,850
From 13,365
View Trip
8 Day France Intensive Voyage with Azamara Cruises
Cruise

8 Days (7 Nights) Monte Carlo to Barcelona
Cruise Line: Azamara Cruises
Ship: Azamara Pursuit
Departure: 06 July 2024
Countries Visited: Monaco, France, Spain
Circle Club Voyage
INSIDE
$2,152
OCEANVIEW
$2,970
BALCONY
$2,716
SUITE
$4,125
From 2,152
View Trip
31 Day Malta, Morocco & Mediterranean with Seabourn
Cruise

31 Days (30 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 21 June 2025
Countries Visited: Italy, Malta, Tunisia, France (+4 more), Spain, Gibraltar, Morocco, Sardinia
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,178
SUITE
$43,028
From 24,178
View Trip
15 Day Mediterranean Rivieras & The Calanques with Seabourn
Cruise

15 Days (14 Nights) Monte Carlo to Monte Carlo
Cruise Line: Seabourn
Ship: Sojourn
Departure: 12 October 2024
Countries Visited: Monaco, Italy, France, Spain (+1 more), Sardinia
More Moments On Us Offer
INSIDE
-
OCEANVIEW
$10,408
BALCONY
-
SUITE
$22,882
From 10,408
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 07 September 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+1 more), France
Exclusive Deal
INSIDE
$2,578
OCEANVIEW
$2,924
BALCONY
$3,271
SUITE
$7,924
From 2,578
View Trip
8 Day Mediterranean Tapestry with Regent Seven Seas
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Navigator
Departure: 15 November 2024
Countries Visited: Italy, France, Spain
Explore More OfferExclusive Deal
INSIDE
-
OCEANVIEW
$3,830
BALCONY
$5,006
SUITE
$5,927
Save 7,440
From 3,830
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Rome to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 13 July 2026
Countries Visited: Italy, France, Corsica, Spain (+3 more), Sicily, Greece, Montenegro
Exclusive Deal
INSIDE
$3,620
OCEANVIEW
$3,867
BALCONY
$4,560
SUITE
$12,381
From 3,620
View Trip
18 Day Mediterranean Delights: Spain, Italy & France with Scenic
New ReleaseCruise

18 Days (17 Nights) Malaga to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 08 April 2026
Countries Visited: Spain, Morocco, Algeria, France (+2 more), Corsica, Italy
Earlybird Saving
INSIDE
-
OCEANVIEW
-
BALCONY
$21,956
SUITE
$34,431
Save 10,634
From 21,956
View Trip
10 Day A Journey from Barcelona to Rome with Explora Journeys
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 14 April 2025
Countries Visited: Spain, Sardinia, Tunisia, Sicily (+1 more), Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$8,118
SUITE
$9,930
From 8,118
View Trip
21 Day Riviera & Mediterranean Magic with Seabourn
Cruise

21 Days (20 Nights) Rome to Monte Carlo
Cruise Line: Seabourn
Ship: Ovation
Departure: 10 August 2025
Countries Visited: Italy, Malta, Tunisia, France (+3 more), Spain, Sardinia, Monaco
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$14,828
SUITE
$28,545
From 14,828
View Trip
16 Day Split to Lisbon with Silversea
Cruise

16 Days (15 Nights) Split to Lisbon
Cruise Line: Silversea
Ship: Silver Dawn
Departure: 12 May 2026
Countries Visited: Croatia, Gibraltar, Italy, Portugal (+4 more), Spain, Tunisia, Malta, Montenegro
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$16,533
BALCONY
$18,810
SUITE
$36,927
From 16,533
View Trip
8 Day Italian Icons: Islands & Culture with Scenic
Cruise

8 Days (7 Nights) Rome to Nice
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 13 May 2025
Countries Visited: Italy, Sardinia, Corsica, France (+1 more), Monaco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,063
SUITE
$14,117
Save 2,602
From 10,063
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,579
BALCONY
-
SUITE
$8,890
Save 1,566
From 6,579
View Trip
8 Day Enchanting Italian Coastlines with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ships: Emerald Sakara
Departures: Aug 2024 to Aug 2026
Countries Visited: Italy, Sardinia, Corsica
Exclusive Deal
INSIDE
-
OCEANVIEW
$6,190
BALCONY
-
SUITE
$9,583
Save 1,577
From 6,190
View Trip
Results: 61-90 of 456

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